miRNAs associated with
Clinical Traits and Diseases
Association of miRNAs with clinical traits and diseases can be investigated through different approaches. In our studies we have tried to identify miRNAs that are associated with divers clinical outcomes by linking plasma levels of circulating miRNAs to the trait/disease of interest or testing the association of miRNA-related SNPs (miRNA-eQTLs, SNPs in miRNA-encoding sequences, or SNPs in the miRNA-binding sites) with the clinical outcome. After detecting an association between a miRNA and disease, we have a pipeline to confirm the association using additional in-silico and in-vtiro experiments, find potential target genes and pathways, and test the biomarker potential of miRNA in a population-based setting. Our studies have so far demonstrated numerous miRNAs to be associated with clinical traits and diseases that are summarized and can be searched by clicking on the name of trait/disease below.
Human Organs
Clinical Traits and Diseases
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